Pharmaceutical Intermediates

6-Amino-5-chloropyrimidine-4-carboxylic acid

6-Amino-5-chloropyrimidine-4-carboxylic acid

Product Name
6-Amino-5-chloropyrimidine-4-carboxylic acid
CAS No.
914916-98-6
Specification
30kg/bag
Category
Pharmaceutical Intermediates

Product Introduction: 6-Amino-5-chloropyrimidine-4-carboxylic acid is a pharmaceutical intermediate of the amino chloropyrimidine carboxylic acid class. It appears as a light yellow to off white powder and contains three derivatizable functional groups: carboxyl, amino, and active chlorine atoms. It is a multifunctional skeleton for synthesizing pyrimidine targeted drugs.

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Product Details

Product Introduction

Product Introduction: 6-Amino-5-chloropyrimidine-4-carboxylic acid is a pharmaceutical intermediate of the amino chloropyrimidine carboxylic acid class. It appears as a light yellow to off white powder and contains three derivatizable functional groups: carboxyl, amino, and active chlorine atoms. It is a multifunctional skeleton for synthesizing pyrimidine targeted drugs.

Specifications

Main indicators: 1. Purity (HPLC): ≥ 98.0% 2. Single impurity: ≤ 0.5% 3. Moisture: ≤ 0.5% 4. Burning residue: ≤ 0.1%

Applications

Usage: Mainly used as a key intermediate for the synthesis of pyrimidine antitumor drugs, antiviral drugs, antibiotics, and cardiovascular drugs; Carboxyl groups can be used for amidation/esterification coupling, chlorine atoms can be replaced by nucleophiles, and amino groups can be diazotized or acylated.

Specification & Packaging

Packaging: Fluorinated plastic bottles or lined iron drums are used for nitrogen sealed packaging, with a net weight of 30kg per bag. Specifications: 30kg per bag, and small packaging (1kg/5kg) can also be provided according to customer needs.

Storage & Transport

Storage, transportation and safety instructions: It is a hazardous chemical. Store in a cool, ventilated, dry, and dark warehouse, away from fire and heat sources, and isolated from strong alkalis, strong oxidants, and combustibles; The packaging must be sealed and filled with nitrogen to prevent moisture absorption and hydrolysis. This product is irritating to the skin, eyes, and respiratory tract. Operators must wear gas masks, goggles, and protective gloves and operate in a fume hood.

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