Pharmaceutical Intermediates

4,5,6-Trichloropyrimidine

4,5,6-Trichloropyrimidine

Product Name
4,5,6-Trichloropyrimidine
CAS No.
1780-27-4
Specification
27kg/bag
Category
Pharmaceutical Intermediates

Product Introduction: 4,5,6-trichloropyrimidine is a chlorinated heterocyclic pharmaceutical/pesticide intermediate, with a white to off white crystalline powder appearance. The three chlorine atoms in the molecule are active and can be selectively substituted by various nucleophiles (amines, alcohols, thiols). It is the core skeleton for synthesizing pyrimidine derived drugs.

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Product Details

Product Introduction

Product Introduction: 4,5,6-trichloropyrimidine is a chlorinated heterocyclic pharmaceutical/pesticide intermediate, with a white to off white crystalline powder appearance. The three chlorine atoms in the molecule are active and can be selectively substituted by various nucleophiles (amines, alcohols, thiols). It is the core skeleton for synthesizing pyrimidine derived drugs.

Specifications

Main indicators: 1. Purity (HPLC/GC): ≥ 99.0% 2. Single impurity: ≤ 0.5% 3. Moisture: ≤ 0.3% 4. Melting point: 67~70 ℃

Applications

Usage: Mainly used as a starting material for the synthesis of pyrimidine antitumor drugs, antiviral drugs, and antibiotics (such as certain kinase inhibitors); It is also a key intermediate for efficient pyrimidine herbicides, fungicides, and insecticides.

Specification & Packaging

Packaging: Fluorinated plastic bottles or lined iron drums are used for nitrogen sealed packaging, with a net weight of 27kg per bag. Specifications: 27kg per bag, and small packaging (1kg/5kg) can also be provided according to customer needs.

Storage & Transport

Storage, transportation and safety instructions: It belongs to irritating and corrosive chemicals. Store in a cool, ventilated, dry, and dark warehouse, away from fire and heat sources, and isolated from strong alkalis, strong oxidants, combustibles, and amines; The packaging must be sealed and filled with nitrogen to prevent moisture absorption. This product is irritating to the skin, eyes, and respiratory tract. When exposed to alkali, it decomposes and releases irritating hydrogen chloride gas. Operators must wear gas masks, goggles, and protective gloves and operate in a fume hood.

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