Pharmaceutical Intermediates

Ethyl 2-(4-(chlorosulfonyl)-2-methylphenoxy)acetate

Ethyl 2-(4-(chlorosulfonyl)-2-methylphenoxy)acetate

Product Name
Ethyl 2-(4-(chlorosulfonyl)-2-methylphenoxy)acetate
CAS No.
91427-62-2
Specification
26kg/drum
Category
Pharmaceutical Intermediates

Product Introduction: Ethyl 2- (4- (chlorosulfonyl) -2-methylphenoxy) acetate is a sulfonyl chloride pharmaceutical intermediate, which appears as white to off white crystals or powders and contains active sulfonyl chloride functional groups. It easily reacts with nucleophilic reagents such as amines and alcohols and is a key intermediate for the synthesis of sulfonamide and glycoside drugs.

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Product Details

Product Introduction

Product Introduction: Ethyl 2- (4- (chlorosulfonyl) -2-methylphenoxy) acetate is a sulfonyl chloride pharmaceutical intermediate, which appears as white to off white crystals or powders and contains active sulfonyl chloride functional groups. It easily reacts with nucleophilic reagents such as amines and alcohols and is a key intermediate for the synthesis of sulfonamide and glycoside drugs.

Specifications

Main indicators: 1. Purity (HPLC): ≥ 98.0% 2. Single impurity: ≤ 0.5% 3. Moisture: ≤ 0.5% 4. Burning residue: ≤ 0.1%

Applications

Usage: Mainly used as a key intermediate for the synthesis of sulfonamide antibiotics, sulfonylurea hypoglycemic drugs, novel antibiotics, and cardiovascular drugs; It is also used for coupling and modification of fine chemicals.

Specification & Packaging

Packaging: Fluorinated plastic bottles or lined iron drums are used for nitrogen sealed packaging, with a net weight of 26kg per drum. Specifications: 26kg per drum, and small packaging (1kg/5kg) can also be provided according to customer needs.

Storage & Transport

Storage and safety instructions: It is a corrosive chemical. Store in a cool, ventilated, dry, and dark warehouse, away from fire and heat sources, and isolated from oxidants, strong alkalis, amines, and combustibles; The packaging must be sealed and filled with nitrogen to prevent moisture absorption and hydrolysis from producing hydrogen chloride. Sulfonyl chloride decomposes into irritating hydrogen chloride gas when it comes into contact with water. Operators must wear gas masks, goggles, and acid resistant protective gloves. They should operate in a fume hood to avoid inhaling vapors and contact with skin and eyes.

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