Pharmaceutical Intermediates

tert-Butyl 2-(2-(2-aminoethoxy)ethoxy)ethylcarbamate

tert-Butyl 2-(2-(2-aminoethoxy)ethoxy)ethylcarbamate

Product Name
tert-Butyl 2-(2-(2-aminoethoxy)ethoxy)ethylcarbamate
CAS No.
153086-78-3
Specification
27kg/drum
Category
Pharmaceutical Intermediates

Product Introduction: 2- (2- (2-aminoethoxy) ethoxy) ethylaminoformate tert butyl ester (Boc-NH-PEG3-CH2CH2NH2) is a bifunctional polyethylene glycol (PEG) pharmaceutical intermediate protected by Boc. It usually appears as a colorless to light yellow transparent liquid or viscous substance, containing free amino groups and Boc protected amino groups, and is soluble in both water and oil.

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Product Details

Product Introduction

Product Introduction: 2- (2- (2-aminoethoxy) ethoxy) ethylaminoformate tert butyl ester (Boc-NH-PEG3-CH2CH2NH2) is a bifunctional polyethylene glycol (PEG) pharmaceutical intermediate protected by Boc. It usually appears as a colorless to light yellow transparent liquid or viscous substance, containing free amino groups and Boc protected amino groups, and is soluble in both water and oil.

Specifications

Main indicators: 1. Purity (HPLC): ≥ 97.0% 2. Single impurity: ≤ 1.0% 3. Moisture: ≤ 0.5% 4. Boc deprotection rate: ≤ 0.5%

Applications

Usage: Mainly used as ADC antibody conjugate drug PROTAC、 Connecting arms for peptide synthesis, protein modification, and nanomedicine delivery systems; It is also a bifunctional linker for the preparation of targeted drugs, PEGylated drugs, carbohydrates, and nucleotide derivatives.

Specification & Packaging

Packaging: Fluorinated plastic bottles or lined iron drums are used for nitrogen sealed packaging, with a net weight of 27kg per drum. Specifications: 27kg per drum, and small packaging (1g/5g/100g) can also be provided according to customer needs.

Storage & Transport

Storage and safety instructions: It belongs to general chemicals. Store in a low temperature, dry, and dark warehouse at 2-8 ℃, away from fire, heat sources, and strong acids (to prevent Boc from deprotection); The packaging must be sealed and filled with nitrogen. This product may cause slight irritation to the skin and eyes. Operators should wear protective gloves, goggles, and masks to avoid inhalation and contact.

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