Pharmaceutical Intermediates

5-Chloro-4-(trifluoromethyl)pyridin-2-amine hydrochloride

5-Chloro-4-(trifluoromethyl)pyridin-2-amine hydrochloride

Product Name
5-Chloro-4-(trifluoromethyl)pyridin-2-amine hydrochloride
CAS No.
1095824-77-3
Specification
29kg/drum
Category
Pharmaceutical Intermediates

Product Introduction: 5-Chloro-4- (trifluoromethyl) pyridine-2-amine hydrochloride is a fluorine-containing chloropyridine pharmaceutical/pesticide intermediate. It appears as a white to off white crystalline powder and contains active amino groups and chlorine atoms. It can undergo further reactions such as diazotization, coupling, and substitution, and is a key building block for the synthesis of various fluoropyridine drugs and pesticides.

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Product Details

Product Introduction

Product Introduction: 5-Chloro-4- (trifluoromethyl) pyridine-2-amine hydrochloride is a fluorine-containing chloropyridine pharmaceutical/pesticide intermediate. It appears as a white to off white crystalline powder and contains active amino groups and chlorine atoms. It can undergo further reactions such as diazotization, coupling, and substitution, and is a key building block for the synthesis of various fluoropyridine drugs and pesticides.

Specifications

Main indicators: 1. Purity (HPLC): ≥ 98.0% 2. Single impurity: ≤ 0.5% 3. Moisture: ≤ 0.5% 4. Melting point: 210~215 ℃ (decomposition)

Applications

Usage: Mainly used as a key intermediate for the synthesis of fluoropyridine based anti-tumor drugs, antiviral drugs, new antibiotics and insecticides, fungicides, and herbicides; Also used for material and ligand synthesis.

Specification & Packaging

Packaging: Fluorinated plastic bottles or lined iron drums are used for nitrogen sealed packaging, with a net weight of 29kg per drum. Specifications: 29kg per drum, and small packaging (1kg/5kg) can also be provided according to customer needs.

Storage & Transport

Storage, transportation and safety instructions: It is a hazardous chemical. Store in a cool, ventilated, dry, and dark warehouse, away from fire and heat sources, and isolated from strong alkalis, strong oxidants, and combustibles; The packaging must be sealed and filled with nitrogen to prevent moisture absorption. This product is irritating to the skin, eyes, and respiratory tract. The hydrochloride form is prone to moisture absorption when exposed to humid air. Operators must wear gas masks, goggles, and protective gloves and operate in a fume hood.

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