![4-Chloropyrrolo[2,3-d]pyrimidine](/uploads/hualun/Uploads/pro_p29.jpg)
4-Chloropyrrolo[2,3-d]pyrimidine
Product Introduction: 4-chloropyrrolo [2,3-d] pyrimidine is a chlorinated bicyclic heterocyclic pharmaceutical intermediate with a white to pale yellow powder appearance. The C-4 chlorine atom is active and easily replaced by nucleophiles such as amines, alcohols, and thiols. It is a key skeleton for the synthesis of purine/pyrrolo pyrimidine targeted drugs (such as JAK inhibitors).
Inquiry NowProduct Introduction: 4-chloropyrrolo [2,3-d] pyrimidine is a chlorinated bicyclic heterocyclic pharmaceutical intermediate with a white to pale yellow powder appearance. The C-4 chlorine atom is active and easily replaced by nucleophiles such as amines, alcohols, and thiols. It is a key skeleton for the synthesis of purine/pyrrolo pyrimidine targeted drugs (such as JAK inhibitors).
Main indicators: 1. Purity (HPLC): ≥ 98.0% 2. Single impurity: ≤ 0.5% 3. Moisture: ≤ 0.5% 4. Melting point: 175~180 ℃
Usage: Mainly used as a key intermediate for the synthesis of JAK inhibitors, anti-tumor targeted drugs, immune modulators, and antiviral drugs (such as fluconazole); It is also used for the development of sugar kinase and Src kinase inhibitors.
Packaging: Fluorinated plastic bottles or lined iron drums are used for nitrogen sealed packaging, with a net weight of 28kg per drum. Specification: 28kg per drum, and small packaging (1kg/5kg) can also be provided according to customer needs.
Storage, transportation and safety instructions: It is a hazardous chemical. Store in a cool, ventilated, dry, and dark warehouse, away from fire and heat sources, and isolated from strong alkalis, strong oxidants, and combustibles; The packaging must be sealed and filled with nitrogen to prevent moisture absorption and hydrolysis. This product is irritating to the skin, eyes, and respiratory tract. Operators must wear gas masks, goggles, and protective gloves and operate in a fume hood.
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